A number of severe side effects can occur if adolescents use AAS.
It has been suggested that the prevalence of use among high-school students in the U. There are four common forms in which AAS are administered: oral pills; injectable steroids; creams/gels for topical application; and skin patches. Testosterone administered by mouth is rapidly absorbed, but it is largely converted to inactive metabolites, and only about one-sixth is available in active form.
These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters, but medical injections are normally done anywhere between semi-weekly to once every 12 weeks.
A more frequent schedule may be desirable in order to maintain a more constant level of hormone in the system.
Studies indicate that the anabolic properties of AAS are relatively similar despite the differences in pharmacokinetic principles such as first-pass metabolism.
However, the orally available forms of AAS may cause liver damage in high doses.