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Addressing these performance characteristics provides assurance that a method meets proper standards of accuracy and reliability.

The testing of the samples can consist of a specific method such as high performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) or a non-specific method such as total organic carbon (TOC), p H and conductivity.

Wetted swabs recover the residue from the surface and solvent extracts the residue from the swab.

The recovery data demonstrates accuracy, precision, linearity and range.

An ARL can be based on available toxicological data such as an allowable daily intake (ADI), an adulteration limit such as 10 ppm and visual cleanliness.

The ARL has a direct bearing on the validation parameters of the test method..

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A residue with no UV chromophore requires either a specialised detector (fluorescence, electrochemical) or derivatisation to achieve the desired sensitivity.

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